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br Liver Fluke Infections and
2018-10-23
Liver Fluke Infections and Cholangiocarcinoma Opisthorchiasis and clonorchiasis are caused by fish-borne liver flukes of the trematode family Opisthorchiidae. >45 million people worldwide are infected by these pathogens. Species of opisthorchiid flukes that cause disease in humans are Opisthorchi
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Pls are a special class
2018-10-23
Pls are a special class of glycerophospholipids characterized by a vinyl ether bond at the sn-1 position of glycerol backbone, and they are sometimes called plasmenyl phospholipid or alkenyl acryl phospholipid. They are found in almost all mammalian tissues and constitute about 18–20% of the total p
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br Materials and Methods br Results br Discussion
2018-10-23
Materials and Methods Results Discussion In our study, we were surprised to find that the transmission is limited to F1 generation. One possible explanation for the limited transmission for enhancement of LTP is that the phenotype ends at a younger age in the offspring of FSs rats than in t
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The aim of this study was to
2018-10-23
The aim of this study was to investigate the impact of therapeutic doses of metformin on uterine pi3k activation and reproductive function, including implantation and pregnancy, under conditions of hyperandrogenism and insulin resistance. We used a rat model in which PCOS-like features can be induc
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Developing an Artificial Bacterial Consortium to Modulate Mi
2018-10-23
Developing an Artificial Bacterial Consortium to Modulate Microbiota of Frail Elderly The microbial composition of the gut changes gradually with aging and is influenced by habitual diet and health status. In one cohort studied, frail elderly had a microbiota profile characterized by an increase in
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In parallel with drug monitoring
2018-10-23
In parallel with drug monitoring, disease monitoring through non-invasive biomarkers plays an important role in IBD patients, as it allows an assessment of the inflammatory burden without the risks involved in colonoscopy-related procedures. Calprotectin constitutes up to 60% of the cytosolic protei
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NAbs occurring after initial infection with HIV are generall
2018-10-23
NAbs occurring after initial infection with HIV-1 are generally not associated with any clinical or biological benefits. Doria-Rose et al. (2010) suggested that the limited breadth of neutralization observed in whole-serum samples from LTNP patients maybe attributable to low levels of antigenic stim
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buy poly ic Until now no valid prognostic
2018-10-23
Until now, no valid prognostic biomarkers for GC chemotherapy have been established, although several potential molecular predictors of recurrence risk and chemotherapy benefit have been investigated (e.g., Ki-67, TS, TP, ERCC1, p21, and immune cell infiltration) (Jiang et al., 2016; Kwon et al., 20
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For the calculation of the bulk value of the
2018-10-23
For the calculation of the bulk value of the Young׳s modulus the simplest choice is a 2-atom tetragonal unit cell with cell vectors along [], [110], and [001]:This cell, however, does not allow to introduce twin boundaries. Therefore, the calculation of was repeated for a second, 6-atom orthorhomb
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br Acknowledgements F Zhu wishes to thank Professor
2018-10-23
Acknowledgements F. Zhu wishes to thank Professor Andrew J. Bell and Dr. Timothy P. Comyn for their professional academic advice and kind support. This work was also sponsored by the National Natural Science Foundation of China (Grants nos. 51332002, 51221291) and the No. 56 Chinese Post-doc Foun
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br Codon usage bias and pathway level
2018-10-23
Codon usage bias and pathway level functions CAI was demonstrated to be positively correlated to relative protein abundance in Leishmania[1]. Hence, assuming CAI to be a predictor of protein expression, we compared CAI values of levomefolic acid belonging to different pathways/processes. For this
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NanoLC MS MS analysis Samples g
2018-10-23
NanoLC-MS/MS analysis. Samples (2µg of yeast cell lysate+different spiked level of UPS1) were analyzed in triplicate by nanoLC-MS/MS using a nanoRS UHPLC system (Dionex, Amsterdam, The Netherlands) coupled to an LTQ-Orbitrap Velos mass spectrometer (Thermo Fisher Scientific, Bremen, Germany). 2µL of
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br Acknowledgements We are very grateful to Lindsay Cowell
2018-10-23
Acknowledgements We are very grateful to Lindsay Cowell and Albert Goldfain for assistance with designing BCIDO. This work was conducted using the Protégé resource, which is supported by Grant GM10331601 from the National Institute of General Medical Sciences of the United States National Institu
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br Data Here we present data
2018-10-23
Data Here, we present data illustrating the inhibitory effects of 18 sugars and 8 glycoproteins (listed in Table 1) on hemagglutination by L-TC, a complex of the botulinum neurotoxin (BoNT), nontoxic nonhemagglutinin (NTNHA), and three types of hemagglutinin subcomponents (HA-70, HA-17, and HA-33
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We refer the reader to
2018-10-23
We refer the reader to the references given in the table for more background on the supplied data. For this dataset, no personal information of the patients is stored or required, with the exception of the CT data. To avoid potential facial recognition, the facial profile of head-and-neck patients i
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