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The miR signature of exosomes isolated from
2019-05-07
The miR signature of exosomes isolated from bulk prostate cancer neuroscience peptides (Fig. 1A, blue cells) and from their cancer stem cell compartment (Fig. 1A, green cells), display high levels of miR-21, miR-30 and miR-218 [23] (Fig. 1A, blue arrow). miR-21 and miR-30 have been identified as key
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Los antecedentes que en este sentido se agradecen son
2019-05-07
Los antecedentes que en este sentido se agradecen son las referencias a los géneros —forense y epidíptico— que convergen en los discursos de quienes presenciaron los acontecimientos de la Conquista. Herencias del medioevo: la tradición bíblica, fábulas y el imaginario pagano, detrás de los que exist
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br In Gretchen Stevens and colleagues update
2019-05-06
In Gretchen Stevens and colleagues\' update of global, regional, and national trends in haemoglobin concentration and levels of anaemia emphasises both the massive extent of the problem, and its very slow rate of improvement. About 30% or more of women and children younger than 5 years are affect
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br Discussion IUI with controlled ovarian
2019-05-06
Discussion IUI with controlled ovarian hyperstimulation has been used over the years as a treatment for mild male factor, anovulation, and unexplained infertility. It is less expensive and less invasive than other assisted reproductive techniques. Therefore, these advantages have made the techniq
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La no intervenci n en los
2019-05-06
La no intervención en los asuntos de otro Estado no significa indiferencia ante los problemas que éste pueda tener. En efecto, algunos usos y gestiones pueden perjudicar equol países vecinos y también al mismo Estado que las realiza. Es por esto que la soberanía no resulta absoluta en lo que respect
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Case report A year old Caucasian male who was
2019-05-06
Case report A 76 year-old Caucasian male who was evaluated in an emergency department due to headache in May 2001 and was found to have a right parietal subdural hematoma (SDH). Baseline blood work revealed thrombocytopenia of 50×109/L. His SDH was managed with surgical evacuation with full recover
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Clinical genetic electrocardiographic and electrophysiologic
2019-05-06
Clinical, genetic, electrocardiographic, and electrophysiological variables did not differ significantly between patients with and without the ER pattern (Table 2). Discussion Among our Brugada syndrome patients, the prevalence of the ER pattern was 10.1%, which is high in comparison to the 2%–5
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One day post implant the
2019-05-06
One day post-implant, the chest X-ray showed the pacemaker lead in place within the RV (Fig. 1b, thick white arrow) with appropriate slack (thin black arrow). The pacemaker parameters were satisfactory and the patient was discharged home on the same day. Two weeks after implantation, after returnin
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br The role of P in
2019-05-06
The role of P62 in tumors The role of P62 in osteoclastogenesis P62 as an oncotarget for treatment Concluding remarks P62 is a cellular “Swiss army knife,” with its diverse cellular functions arising from its unique functional motifs and protein–protein interaction properties. P62 may pl
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Benjam n Arditi por su parte ha
2019-05-05
Benjamín Arditi, por su parte, ha desarrollado parte de su obra en diálogo con y contra Laclau. En lo que nos ocupa, en una extensa reseña de La razón populista, Arditi repara en la triple sinonimia de populismo, hegemonía y política y, además, lanza un conjunto de observaciones agudas. Al igual que
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In an earlier study we used a questionnaire to assess
2019-05-05
In an earlier study, we used a questionnaire to assess musculoskeletal pain in patients with CML who had achieved DMR (MR4.0) and discontinued TKI treatment, including IM, nilotinib, and dasatinib [5]. Nine out of the 27 patients surveyed developed musculoskeletal pain after discontinuing TKIs. In t
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melanin The study by Mijiti and
2019-05-05
The study by Mijiti and colleagues also illustrates that, besides medical factors, social determinants of health—poverty, education, geography, customs, etc—also play an important role in tuberculosis control. Owing to the low socioeconomic status and poor social health environment, tuberculosis mai
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In an early meta analysis diagnosing cancer of the
2019-05-05
In an early meta-analysis, diagnosing cancer of the pancreas by ERCP with the “double duct” sign had a sensitivity of 92% and specificity of 96%. In the present case, mild proximal CBD dilatation with an abrupt distal CBD stricture was detected by ERCP. The most common malignant cause of obstructive
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Data for each assessment point
2019-05-05
Data for each assessment point are expressed as the mean value plus standard deviation. One tailed paired t-tests were performed to analyze the effects of ibandronate treatment. Significance level was set at p Results The study included 33 patients with a variety of different primary tumors (Table
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Any abnormality causing a loss
2019-05-05
Any abnormality causing a loss-of-function in the IKs macromolecular complex may lead to adrenergic-induced imbalance in ventricular repolarization currents and consequent QTc prolongation, which is identified based on the defective response of IKs to PKA stimuli due to mutations in KCNQ1 (-G269S, -
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