• Introduction Myelodysplastic Syndrome MDS is a heterogeneous

  2019-04-23

  

  Introduction Myelodysplastic Syndrome (MDS) is a heterogeneous clonal disorder characterized by ineffective hematopoeisis and propensity for transformation into Acute Myelogenous Leukemia (AML). The Revised International Prognostic Scoring System (R-IPSS) is an accepted model used to predict overal

• br The paper in by Victoria Fan and colleagues is

  2019-04-22

  

  The paper in by Victoria Fan and colleagues is important because it describes what several people close to the Global Fund to fight AIDS, Tuberculosis and Malaria already know: there is a problem with its disbursement mechanisms. Fan and colleagues correctly state that the Global Fund should “red

• Our patient a year old woman arrived in Italy from

  2019-04-22

  

  Our patient (a 24-year-old woman) arrived in Italy from Eastern Europe in March 2013 as an illegal immigrant. Three months later she was admitted to our hospital. Her blood counts were as follows: leukocytes 410.7×109/L, platelets 391×109/L, Hb 11g/dl, with immature myeloid Silmitasertib at differe

• Macrophages in bone metastasis main outstanding questions

  2019-04-22

  

  Macrophages in bone metastasis – main outstanding questions: Conflict of interest statement Acknowledgements IV was supported by a generous grant from Weston Park Hospital Cancer Charity, Sheffield, UK. Introduction In recent years there has been increasing interest in the role of bone-ta

• br Results br Discussion br

  2019-04-22

  

  Results Discussion Conclusions Disclosures Conflict of interest Financial support Introduction Stroke is one of the top five common causes of mortality in Malaysia with a rate at 8.43/100,000 ack1 inhibitor [1,2]. Stroke impact is not limited to physical disabilities that strok

• Concurrent with the clinical evaluation

  2019-04-22

  

  Concurrent with the clinical evaluation of the family, the genetic findings from a molecular autopsy may help to elucidate the cause of death in the decedent, as well as provide a basis for cascade genetic testing of at-risk family members. Offering cascade genetic testing to asymptomatic relatives

• Despite our best efforts the cause of SCD in young

  2019-04-22

  

  Despite our best efforts, the cause of SCD in young individuals is sometimes not established; no cause is identified in up to 40% of cases. Importantly, whether a cause of death is established or not, the possibility of an underlying inherited cardiac disorder remains in many cases, including the po

• silybin The exact location of the APs within the

  2019-04-22

  

  The exact location of the APs within the cusps is difficult to determine. The majority of studies used coronary angiography, and less commonly electroanatomical mapping. The morphology of local atrial and ventricular electrograms may be additionally used [1,2]. Mapping within the RCC typically shows

• OS is Executive Director of the INDEPTH Network PB

  2019-04-22

  

  OS is Executive Director of the INDEPTH Network. PB is Director of the WHO Collaborating Centre for Verbal Autopsy and chairs the Scientific Advisory Committee of the INDEPTH Network. The INDEPTH Network is grateful for core funding from Sida, the Wellcome Trust, and the William & Flora Hewlett Foun

• Ethiopia is faced with challenging circumstances It is

  2019-04-22

  

  Ethiopia is faced with challenging circumstances. It is a low-income country, with a gross domestic product estimated by the International Monetary Fund at US$570 per person in 2014, and 66% of the keap1 nrf2 living on less than US$2 per day in 2011—rates that are even lower than the averages for s

• In Blake Alkire and colleagues now provide additional measur

  2019-04-22

  

  In , Blake Alkire and colleagues now provide additional measures to help us gain political priority on the public health agendas. In this study, Alkire and colleagues modelled access to surgery in 180 countries on the basis of four criteria: timeliness, surgical capacity, safety, and affordability.

• Esta parte de la cr

  2019-04-22

  

  Esta parte de la crítica a la que aludo, en aquel entonces, se orienta hacia el replanteamiento de la función social de la literatura y el cuestionamiento epistemológico de la práctica crítica misma. Incidiendo en este aspecto, George Gugelberger llega a afirmar lo siguiente: “Thus, the testimonio b

• br It is encouraging to read in the Article by

  2019-04-22

  

  It is encouraging to read in the Article by Mercy Kanyuka and colleagues (March, 2016) about Malawi\'s success in reducing child mortality, but I fear the authors might have missed one of the key factors contributing towards this great achievement. Specifically, that Malawi is unique in sub-Sahara

• On what might an argument for a fairer distribution

  2019-04-22

  

  On what might an argument for a fairer distribution of malaria research investment rest? The investments analysed by Head and colleagues were those made from outside of sub-Saharan Africa, not by African countries themselves, and were a mix of public funds channelled through bilateral and multilater

• Conflicts of interest br Introduction Hepatocellular

  2019-04-22

  

  Conflicts of interest Introduction Hepatocellular carcinoma (HCC) is one of the most common cancers and is the second leading cause of cancer death worldwide. In 2012, 782,500 new HCC cases and 745,500 deaths were caused by this persistent disease worldwide, with about 50% of the total number of

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