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Although the NCCN IPI is a promising simple scale based
2019-05-10
Although the NCCN-IPI is a promising simple scale based on conventional clinical factors, its usefulness remains controversial [6,7]. It should be evaluated in populations of different regions and ethnicities before adopting it for routine clinical use. Conflict of interest Report At presenta
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br Discussion Case reports of successful chemotherapy desens
2019-05-10
Discussion Case reports of successful chemotherapy desensitizations have been described for platinum agents, taxanes, anthracyclines, rituximab [8], and cytarabine [9], but not specifically clofarabine. For older patients with relapsed AML that are not candidates to receive anthracycline therapy,
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Diagnosis of pituitary metastasis could be
2019-05-10
Diagnosis of pituitary metastasis could be missed by medical practitioners because most patients who developed pituitary metastasis are clinically asymptomatic. Patients may have signs and symptoms of nausea, vomiting, fatigue, and weight loss, which could also be viewed as pan-hypopituitarism, and
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br Case report At that time her
2019-05-09
Case report At that time, her laboratory examinations showed hemoglobin (Hb) of 10.4 g/dl (normal: 11.3–15.3), and platelets of 36,000/mm3 (normal: 150,000–400,000), and WBC count of 3800/mm3 (normal: 4000–11,000). The liver function showed serum albumin was 3.2 g/dl, total bilirubin was 1.7 mg/d
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There are few learning points that can be
2019-05-09
There are few learning points that can be derived from this case. While VDD is an acceptable mode in young patients, one should be cautious of using this mode in elderly patients with sick sinus syndrome, unless retrograde VA conduction is absent. A single PVC can trigger a ventricular paced rhythm
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Rulfo emplea un s mil para describir la ca
2019-05-09
Rulfo emplea un símil para describir la caída de Pedro Páramo, para crear el efecto de desmoronamiento del personaje. El lector o la lectora “oyen” la caída de ese cuerpo. Acompañado por una muerta, Damiana Cisneros, que en la posición de Caronte le invita al mundo de los muertos, Pedro Páramo se de
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ret pathway Poor knowledge among caretakers of how to work w
2019-05-09
Poor knowledge among caretakers of how to work with disability-related disorders could also be an issue. For example, poor knowledge of how to correctly position a child with severe cerebral palsy could lead to inadequate feeding; at worst, these efforts can cause aspiration and even death. Social a
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Un ciclo diferente y mucho m
2019-05-09
Un ciclo diferente y mucho más profundo de transformaciones se inicia con el proceso constitucional en Bolivia y Ecuador. Bolivia se “re-funda” en 2009 y se proclama Estado Unitario Social de Derecho Plurinacional Comunitario. El capítulo cuarto sobre los derechos de las naciones y pueblos indígenas
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As Table shows all guidelines recommend
2019-05-09
As Table 2 shows, all guidelines recommend OACs for patients with a CHADS2 score of ≥2, whereas recommendations for low-risk patients with a CHADS2 score of 0/1 differ slightly across guidelines. Evidence indicating that novel OACs decrease the risk of ICH by half as compared with warfarin has affec
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br Discussion We describe an
2019-05-09
Discussion We describe an additional diagnosis to consider when BVT is identified. One of the proposed mechanisms of BVT include elevated intracellular calcium, causing delay after depolarization in anatomically separate parts of the conducting system. Baher et al. [1] proposed that two separate
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The studies from several laboratories suggest that miR
2019-05-08
The studies from several laboratories suggest that miR-34 family members are the direct targets of TP53, and their upregulation can induce cancer cell apoptosis and cell-cycle arrest. It has been found that miR-34 is associated with prognosis, carcinogenesis, and survival of various cancers, includi
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Reviewing the literature we knew that in cases of AA
2019-05-08
Reviewing the literature, we knew that in cases of AA, use of IST should be cautious, as IST might accelerate occult lymphoma escaping immune surveillance and evolving as a refractory lymphoma. Second, in cases of AA and concomitant NHL, to choose cytotoxic chemotherapy or IST is an art. Depending o
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In this case series no clinical thromboembolic
2019-05-08
In this case series, no clinical thromboembolic events were detected in a cohort with a mean CHA2DS2-VASc score of 2.6 ±1 over a follow-up time of up to 5 years. The overall stroke rate was 0.5% per year. The authors concede that the very low stroke rate could have been the outcome of successful abl
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br The estimated number of
2019-05-08
The estimated number of women who die each year from causes related to pregnancy or childbirth has dropped substantially—from 543 000 deaths in 1990 to about 287 000 in 2010. Nevertheless, maternal mortality ratios remain among the least equitable of all health indicators, ranging from less than f
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br Consideracj es fin is De acordo com as
2019-05-08
Consideracjóes fináis De acordo com as evidências coletadas com Gefitinib manufacturer pesquisa, algumas discussões passam a ser sugeridas. Inicialmente, das parcerias entre Estado e sociedade foram abertas vagas na saúde públicas a serem ocupadas por “pessoas jurídicas de direito privados”, e me
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