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In this study we analyzed the biological effects of
2019-04-20
In this study, we analyzed the biological effects of two novel GATA2 mutations, which were identified in adult de novo AML patients. Materials and methods The diagnosis of AML was based on the morphology, histopathology, the expression of leukocyte differentiation niclosamide and/or the French–
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Regarding the expression of NKp
2019-04-20
Regarding the expression of NKp46/NCR1 (Fig. 1A and B), both increased and decreased expression are observed depending on patients. Interestingly, the expression of the inducible molecule NKp44/NCR2 is clearly induced in 3 patients (PT1, PT2 and PT5) both regarding the percentage and the MFI. In con
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One year after her initial
2019-04-20
One year after her initial diagnosis, the patient presented back for the abrupt onset of symmetrical bilateral lower-limb weakness and numbness. The patient did not report other symptoms or history of trauma. Clinical examination revealed a healthy person except for a symmetrical proximal and distal
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purchase everolimus br Drug resistance In clinical practice
2019-04-20
Drug resistance In clinical practice, there is no cross–drug-resistance between As2O3 and RA or other antileukemic agents. This may be explained by the non-liposoluble nature of As2O3, its small molecular weight, and its distinctive modes of action [20]. In our observation, primary As2O3 resistan
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br In the cluster randomised controlled
2019-04-20
In the cluster randomised controlled trial by Marcel Yotebieng and colleagues (August, 2015) the addition of Step 10 of the UNICEF Baby Friendly Hospital Initiative (BFHI)—that is, the provision of additional support for breastfeeding—did not enhance the effects of steps 1–9, and may even have les
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After a decade of political and economic crisis
2019-04-20
After a decade of political and economic crisis between 1999 and 2010, health education in Zimbabwe was in a desperate state and required a major overhaul. UZCHS reported a 60% decrease in medical student enrolment, a 61% faculty vacancy rate, a 50% increase in failure rate, and the specialist train
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Para tratar de explicar el inter s de la dfs
2019-04-19
Para tratar de explicar el interés de la dfs en estos contactos con Cuba debemos comprender las complejas relaciones establecidas entre el México priista y la Revolución castrista. La posición oficial de México respecto CX5461 la Revolución cubana en materia de relaciones internacionales era bastant
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br Discussion ATRA and arsenic are both known to
2019-04-19
Discussion ATRA and arsenic are both known to induce differentiation syndrome but this case was notable for its severity. Previous studies of differentiation syndrome have demonstrated that APL RGFP966 Supplier treated with ATRA secrete the chemokines CCL2 and IL-8, which in combination with che
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AZD-9291 Premature deaths of women have profound effects
2019-04-19
Premature deaths of women have profound effects on families, societies, and economies, regardless of the age at which they occur and whatever the cause, including an—often preventable—NCD or injury later in life. Families, especially if female-headed, are driven into poverty through catastrophic hea
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br Conclusions br Financial support br Conflict
2019-04-19
Conclusions Financial support Conflict of interest Acknowledgment Introduction Cardiac resynchronization therapy (CRT) has been demonstrated to improve symptoms, quality of life, functional status, and reduce mortality and Cy3-dCTP failure-related hospitalizations in patients with New
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Pain flare defined as a temporary worsening
2019-04-19
Pain flare, defined as a “temporary worsening of bone pain in the treated metastatic site” [2], has been previously documented as a side effect of radiopharmaceutical and hormonal therapy [2,10,11]. Although it is a recognized side-effect of radiation treatment as well, only recent studies have atte
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br Material and methods br Results
2019-04-19
Material and methods Results Discussion Previously, various small studies reported that CRT is an effective therapy in patients with NAHF [7,10–15]. These studies demonstrated favorable outcomes in patients treated with CRT, including the ability to wean patients from intravenous inotropes
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On the other hand it has been reported that
2019-04-19
On the other hand, it has been reported that the Purkinje network can survive in patients with ischemic or idiopathic cardiomyopathy [6], and in patients with GSK503 failure and left bundle branch block (LBBB). In addition, idiopathic LV tachycardia that involves the Purkinje network as the circuit
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Con Lemebel y Perlongher y la resonancia
2019-04-18
Con Lemebel y Perlongher, y la resonancia que en ellos tienen Gilíes Deleuze y Félix Guattari, puede percibirse un gesto de queeridad sudamericano, un “infinito devenir minoritario, nómade, siempre en movimiento, en el que podemos leer la emergencia de una mirada que se acerca overseas lo queer de m
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Chronic hepatitis B virus HBV infection
2019-04-18
Chronic exportin virus (HBV) infection is prevalent in many Asian countries, notwithstanding three decades of universal hepatitis B vaccination programs. The invention of nucleos(t)ide analogs (NUCs) was a breakthrough in the treatment of chronic hepatitis B (CHB). However, HBV continues to be a ch
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